Older adults with amnestic mild cognitive impairment (aMCI) who engaged in structured physical activity, including moderate-to-high intensity aerobic training or low-intensity stretching, balance, and range-of-motion activities, showed significantly less cognitive decline compared to sedentary individuals who received no intervention. Brain imaging revealed less shrinkage in the entorhinal cortex, a memory-related region, in the aerobic exercise group. Both exercise interventions were found to be beneficial compared to no exercise, with supervised activity being key to participant adherence.

Source: Alzheimer’s & Dementia