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Conexiant chevron_right Neurology chevron_right New Tau Phosphorylation Sites Linked to Early Alzheimers
From the Journals

New Tau Phosphorylation Sites Linked to Early Alzheimer's

Phospho-tau serine-262 and serine-356 detect prefibrillar tau aggregates, offering early diagnostic potential in Alzheimer's disease

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article Full Article subject Summary summarize Notecard
  1. Phosphorylation at serine-262 and serine-356 on tau protein identified as early biomarkers for Alzheimer's disease.
  2. Cerebrospinal fluid assay has potential to distinguish AD from non-AD tauopathies.
  3. Findings suggest diagnostic biomarker and therapeutic opportunities for AD.
  4. Cerebrospinal fluid assay correlated with NFT burden, cognitive decline, and tau PET uptake across Braak NFT stages.

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