- Muscle ultrasound has revealed distinct fasciculation differences between ALS and SBMA patients.
- A modified ultrasound scoring system effectively distinguishes ALS from SBMA.
- Ultrasound can complement clinical and electrophysiologic findings but should not replace existing diagnostic methods.
- SBMA patients showed more tongue fasciculations, while ALS patients exhibited widespread and more intense fasciculations.
- Age and disease duration varied between the SBMA and ALS groups.
- Ultrasound can serve as a useful noninvasive tool in differentiating ALS from SBMA.
- No statistically significant correlations were found between fasciculation characteristics and clinical measures.
- The absence of tongue muscle fasciculations on ultrasound may exclude SBMA from the diagnosis.
Source: BMJ Neurology Open