- A systematic review of 14 studies analyzed data from over 130 million patients regarding the relationship between dementia risk and certain medications.
- Antimicrobials, anti-inflammatories, and vaccines were associated with reduced dementia risk.
- Antipsychotics, antidepressants, and diabetes medications were frequently associated with increased dementia risk.
- Reverse causation is a concern, as these medications may be prescribed for early dementia symptoms.
- Research suggests the need for further investigation to refine causal inference and assess potential drug repurposing strategies.
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