In a single-center retrospective study, an internally validated model using radiologist-assessed imaging features and clinical data showed moderate discrimination of arthroscopic meniscal repairability.
A Swiss registry study found that the wrist and second and third metacarpophalangeal joints consistently resolved more slowly than most other joints following biologic or targeted synthetic therapy.
Two single-injection cross-linked hyaluronic acid formulations showed no statistically significant advantage over saline for pain or functional outcomes through 24 weeks.
Investigational inhibitor was not associated with treatment-related serious adverse events and produced biomarker changes consistent with pathway inhibition in healthy volunteers.
Conexiant
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Nearly 90% of patients who met algorithmic criteria for postacute sequelae of SARS-CoV-2 infection had at least 1 chronic or potentially chronic condition requiring ongoing clinical management.
A meta-analysis of placebo-controlled crossover trials found reduced aerobic time-trial completion times with both low- and moderate-dose oral anhydrous caffeine, but the evidence was mostly derived from male participants, cycling studies, and trials using doses no higher than 6 mg/kg.
A review of 56 qualitative studies found residents' emotional experiences were influenced by interactions among training demands, workplace relationships, and their evolving professional identity.
Preoperative use was associated with fewer revisions and no increase in short-term complications among patients with obesity, although benefits appeared concentrated in select subgroups.