June 29, 2026

Low-Dose Caffeine May Improve Aerobic Time-Trial Performance

A meta-analysis of placebo-controlled crossover trials found reduced aerobic time-trial completion times with both low- and moderate-dose oral anhydrous caffeine, but the evidence was mostly derived from male participants, cycling studies, and trials using doses no higher than 6 mg/kg.

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June 26, 2026

Identity Formation May Shape Residency Emotions

A review of 56 qualitative studies found residents' emotional experiences were influenced by interactions among training demands, workplace relationships, and their evolving professional identity.

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June 24, 2026

Do Revisions in Rotator Cuff Repair Decline With GLP-1 Use?

Preoperative use was associated with fewer revisions and no increase in short-term complications among patients with obesity, although benefits appeared concentrated in select subgroups.

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June 23, 2026

Risks of Mobility Decline After Hip Fracture

Danish registry study found no consistent association between mobility recovery and reoperation, but mortality increased as mobility loss worsened.

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June 23, 2026

Side Effects: Sour Mouth, Lower BP

Acidic gum beat sugar-free at cranking out nitric oxide from beetroot juice — exactly backward from what test-tube studies predicted. Also this week: a sleep gene that ignores amyloid, and jackfruit sap moonlighting as a bone-building drug delivery system.

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June 22, 2026

FDA Clears Olastrocel Trial Expansion

Additional patients with ongoing opioid use are being enrolled as Creative Medical prepares for potential Phase 3 discussions with the FDA.

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June 22, 2026

PRP Linked to Better Outcomes in Advanced Knee OA

In a small open-label randomized trial, 2 platelet-rich plasma injections were associated with greater 6-month improvements in pain and function than corticosteroid injection or oral aceclofenac among patients awaiting knee arthroplasty.

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June 18, 2026

Cell Aging May Predict Future Disease

Plasma proteomic models of more than 40 cell types were associated with incident Alzheimer's disease, amyotrophic lateral sclerosis, cancer,  and mortality across three large cohorts.

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June 16, 2026

Self-Management May Reduce Chronic Low Back Pain

In a randomized clinical trial of patients at increased risk for persistent symptoms, clinician-supported biopsychosocial self-management was associated with lower pain impact and fewer chronic pain outcomes than guideline-based medical care.

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June 15, 2026

RA Genetics May Reveal Link to Gum Disease

Analysis of East Asian genetic data found a modest inverse association between rheumatoid arthritis susceptibility and periodontitis risk, though researchers said the findings require confirmation in independent cohorts.

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