December 20, 2024

Will CAR T-Cell Therapy Be the Magic Bullet for My Multiple Myeloma?

“Intense pain on the right side of my lower rib cage, in 2020, sent me first to my chiropractor for relief and then to my primary care provider for tests. Because of the location of the pain, the chir...

The ASCO Post

December 20, 2024

Riluzole Shows Promise in Reversing Cognitive Decline from Radiation Therapy

Boosting brain-derived neurotrophic factor (BDNF) with riluzole may mitigate cognitive dysfunction from radiation therapy.

Conexiant

December 20, 2024

Study Finds Daratumumab Monotherapy Prevented or Delayed Progression From Smoldering to Active Multiple Myeloma

The ongoing randomized phase III AQUILA study found that daratumumab monotherapy was well tolerated and demonstrated a clinically meaningful and significant benefit in preventing or delaying progressi...

The ASCO Post

December 20, 2024

Small HCQ Study Falls to Retraction

When combining hydroxychloroquine with azithromycin, researchers reported 100% virological cure by day 6 compared to 57.1% with hydroxychloroquine alone and 12.5% in controls - though the now-retracted study's small sample included just 6 patients receiving both drugs.

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December 20, 2024

In Treatment of Transplant-Ineligible Myeloma, Addition of Isatuximab Improves Outcomes

In the phase III IMROZ trial, the addition of the anti-CD38 monoclonal antibody isatuximab-irfc to bortezomib, lenalidomide, and dexamethasone (VRd) was more effective than VRd alone as initial therap...

The ASCO Post

December 20, 2024

Use of Ibrutinib in Early-Stage Chronic Lymphocytic Leukemia

In a German phase III trial (CLL12), reported in the Journal of Clinical Oncology, Langerbeins et al found that ibrutinib prolonged the time to symptomatic disease in patients with early-stage chronic...

The ASCO Post

December 20, 2024

Introducing the Quirky Clinic

Each week we’ll dive into the strangest and most surprising medical stories, from cutting-edge science to unbelievable true tales.

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December 20, 2024

Long COVID Shows Five Distinct Patterns: Study

In the 2024 update, the NIH's RECOVER Initiative identified five distinct symptom patterns and new diagnostic thresholds for long COVID.

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December 20, 2024

POI Guidelines See First Major Update Since 2015

Four medical societies have revised their diagnostic criteria for premature ovarian insufficiency, now requiring only one elevated FSH test instead of two, while reporting a higher than previously known prevalence rate of 3.5% among women.

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