- Smoking, high BMI, and alcohol use significantly contribute to colorectal cancer-related deaths, particularly in low socioeconomic regions.
- Smoking-related colorectal cancer mortality has decreased in high-income countries but is projected to rise in lower-income regions.
- Men have substantially higher mortality rates than women for all three risk factors.
- Colorectal cancer mortality rates vary by development level, with high-income countries showing declining rates.
- The study recommends targeted public health strategies focusing on smoking cessation, alcohol moderation, and BMI reduction for preventing and detecting colorectal cancer.
Source: Frontiers in Oncology