5 Key Takeaways

• 1

  Financial conflicts of interest for US vaccine advisory committees have decreased significantly over the past 25 years.

• 2

  ACIP's reported conflicts of interest dropped from 43% in 2000 to 5% in 2024.

• 3

  VRBPAC's conflict rates peaked at 27% in the early 2000s but have remained under 4% since 2010.

• 4

  The most common conflicts involved research support, consulting, and stock holdings, with income-related conflicts below 1% since 2016.

• 5

  ACIP's decline in reported conflicts was statistically significant, while VRBPAC's decline was not, despite low rates in recent years.