Fetal hematopoietic stem cells in Down syndrome are 'primed' for differentiation, as revealed by single-cell multi-omics of over 1.1 million cells, potentially explaining early hematological abnormalities.
A recent study reveals that older adults with a history of epilepsy face a heightened risk of cardiovascular events, with medication use playing a significant role in this association.
A meta-analysis of 11 trials found that bright light therapy significantly improved remission rates in nonseasonal depression, with 40.7% of patients achieving remission compared to 23.5% in control groups.
In a phase 3 trial, 67% of children treated with omalizumab tolerated 600 mg of peanut protein, a dramatic increase over just 7% with placebo, highlighting omalizumab’s potential in managing pediatric food allergies.
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Patients with both obesity and diabetes saw a 2.53-fold increase in hepatocellular carcinoma recurrence beyond five years post-surgery, highlighting the critical impact of these comorbidities on long-term outcomes.
A nationwide study of over 10 million privately insured individuals found that colorectal cancer screening uptake among 45- to 49-year-olds tripled after the 2021 USPSTF recommendation, with 13.9% receiving screening before age 50.
Study reveals 37.9% of single emerging adults are relatively happy, challenging stereotypes and highlighting the crucial role of friendship satisfaction in their well-being.
A cluster randomized trial found that a group parenting intervention for fathers with postpartum depression led to significant improvements in paternal mental health and child social-emotional development, with 75% of participants attending 10 or more of the 12 sessions.