A randomized trial found similar short-term morbidity and 12-month functional outcomes with both approaches, while highlighting the need to balance perfusion with a tension-free anastomosis.
In a planned BALANCE analysis, elevated day 7 procalcitonin was associated with higher mortality, but the small subgroup analysis found no evidence that extending antibiotics from 7 to 14 days improved outcomes.
A matched electronic health record study of more than 876,000 patients with type 2 diabetes found a low absolute incidence but higher relative hazard of documented smell and taste disturbances among patients prescribed glucagon-like peptide-1 receptor agonists.
A JAMA Internal Medicine Viewpoint urges clinicians and health systems to verify risk-model inputs before acting on automated breast cancer screening recommendations.
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Acidic gum beat sugar-free at cranking out nitric oxide from beetroot juice — exactly backward from what test-tube studies predicted. Also this week: a sleep gene that ignores amyloid, and jackfruit sap moonlighting as a bone-building drug delivery system.
A single-center editorial described real-world integration of artificial intelligence–based coronary artery calcium scoring into routine cardiac CT workflow, with researchers reporting rapid report availability and high agreement with manual reference standards while emphasizing continued radiologist oversight.
A first-of-its-kind randomized trial in in-hospital cardiac arrest found no statistically significant increase in sustained return of spontaneous circulation with sodium bicarbonate vs placebo.