July 23, 2025

NSCLC Trial Shows Radiation May Overcome Primary Resistance to Pembrolizumab

The addition of radiation may be able to surmount resistance to immunotherapy for some more immunologically “cold” tumors, as suggested by the findings of a study focused on the immunomodulatory effec...

The ASCO Post

July 23, 2025

Association of Type 2 Diabetes With Colorectal Cancer Risk and Survival by Tumor Immunity Status

In a German population–based, matched case-control study reported in the Journal of Clinical Oncology, Wankhede et al found that type 2 diabetes is associated with colorectal cancer (CRC) risk and sur...

The ASCO Post

July 23, 2025

HER2DX Assay and Survival Outcomes in HER2-Positive Breast Cancer

In an individual patient-level meta-analysis reported in The Lancet Oncology, Villacampa et al found that the HER2DX assay risk score was prognostic for event-free survival outcomes in patients with e...

The ASCO Post

July 23, 2025

Noncovalent BTK Inhibitor in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

In a phase III trial (BRUIN CLL-321) reported in the Journal of Clinical Oncology, Sharman et al compared treatment outcomes with the noncovalent BTK inhibitor pirtobrutinib vs investigator choice of ...

The ASCO Post

July 23, 2025

Frontline Triplet Regimens for Intensive Chemotherapy-Ineligible IDH-Mutant AML

In a single-center study reported in the Journal of Clinical Oncology, DiNardo et al investigated whether frontline triplet regimens consisting of a hypomethylating agent, venetoclax, and an isocitrat...

The ASCO Post

July 23, 2025

6 Blood Proteins Predict Kidney Function Decline

A 6-protein blood-based model predicted kidney function decline in patients with ADPKD more accurately than clinical or imaging-based models, and offers a new pathway for outcome prediction.

Conexiant

July 23, 2025

Fox Chase Takes Center Stage at 2025 National Meetings

Fox Chase surgical fellows and faculty pave the way for better cancer outcomes with research presented at SSO, ASCO, AUA, and SSO.

Fox Chase Cancer Center

July 23, 2025

Diet Linked to Crohn’s Risk but Not Ulcerative Colitis, Meta-analysis Finds

A new meta-analysis of 2,043,601 people found that diets high in fiber and minimally processed foods may lower the risk of Crohn’s disease, while inflammatory and ultra-processed diets were linked to increased risk.

Conexiant

July 23, 2025

Ultrasound Combo Detects MASH and Fibrosis

Two ultrasound techniques show strong diagnostic performance for steatohepatitis and fibrosis, supporting a noninvasive alternative to biopsy.

Conexiant