Circulating Insulin-like peptide 5 concentrations may reflect colonic exposure to bile acids and help stratify treatment response in patients with chronic diarrhoea, including those with irritable bowel syndrome with diarrhoea and bile acid diarrhoea.
A 3-year analysis of a phase IIIb trial found that bimekizumab, a dual interleukin-17A and interleukin-17F inhibitor, maintained high rates of skin clearance and demonstrated a consistent safety profile in patients with moderate-to-severe plaque psoriasis, including those who switched from secukinumab, an interleukin-17A inhibitor.
Randomized trial results showed that modified open mesh repair was as safe and effective as standard mesh repair for treating groin hernias in women, with similar recurrence and complication rates after 1 year.
A new meta-analysis of 11 randomized controlled trials found that patients began regaining weight as early as 8 weeks after discontinuing anti-obesity medications, with weight gain continuing through 52 weeks.
Researchers will systematically review the efficacy and safety of acupuncture for abdominal pain in IgA vasculitis, aiming to inform clinical practice.
The Colorectal Cancer Alliance and partners are urging the Department of Health and Human Services to preserve U.S. Preventive Services Task Force’s evidence-based role in safeguarding access to no-cost colorectal cancer screening.
An international cohort study found that patients with sludge- or microlithiasis-induced acute pancreatitis had significantly fewer long-term complications than those with gallstone-related pancreatitis.