Researchers urge physicians to reconsider diphenhydramine use due to safety concerns, high sedation risk, and safer second-generation antihistamine alternatives.
Clinical practice guideline sets performance thresholds for blood-based biomarkers to assist Alzheimer’s diagnosis in specialty care, with conditional support and emphasis on clinical context.
Guided lifestyle coaching delivers measurable cognitive improvements over two years, suggesting structure and accountability enhance intervention outcomes in at-risk older adults.
National mortality data reveal that surgeons face higher death rates than non-surgeon physicians, with cancer and external causes contributing prominently.
Estradiol increases susceptibility to retinal degeneration in female mice with retinitis pigmentosa, highlighting hormone-specific effects on neurodegenerative disease pathways.
Study finds cognitive performance declines more sharply with worsening hearing among older adults who experience loneliness despite being socially connected.
Neuroimaging detects reduced grey matter in multiple brain regions among breast cancer patients after chemotherapy, raising concern for long-term cognitive risks.