New EULAR criteria classify hand osteoarthritis phenotypes using radiographic features, enabling more targeted clinical trials for specific joint involvement patterns.
A systematic review of 439 studies reveals high-quality evidence supporting biologic therapies and defined treatment targets for systemic lupus erythematosus, with anifrolumab and belimumab showing superior efficacy to standard care in extrarenal disease.
EULAR's latest recommendations for systemic sclerosis treatment include 22 evidence-based guidelines across 8 clinical domains, marking a significant expansion from the 16 recommendations in 2017.
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The updated SCAI guidelines emphasize transradial access as the preferred route for coronary angiography and PCI in STEMI patients, citing a meta-analysis from randomized trials showing lower mortality and major bleeding compared to femoral access.
"As prescription opioids increasingly became involved in U.S. overdose deaths, the proverbial pendulum swung widely, and many clinicians and health systems inflexibly began refusing to offer opioids for pain."