- Patients with eczema, asthma, or other atopic conditions had higher postoperative risks across both implant-based breast reconstruction and bone graft procedures.
- Atopic skin disease was associated with increased implant infections, rupture, capsular contracture, and revision surgery up to three years after breast reconstruction.
- In bone graft recipients, atopic disease increased risks of infection, osteomyelitis, mechanical loosening, and hardware removal at 90 days and 2 years.
- Immune dysregulation in atopic disease may impair wound healing and raise susceptibility to postoperative complications.
- Surgical teams should consider atopic status in preoperative risk assessment, counseling, and postoperative monitoring.
Source: 2025 Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology