- A 16-week randomized trial showed a Mediterranean diet program reduced psoriasis severity compared with low-fat dietary advice.
- Nine of 19 patients in the diet group achieved PASI 75, while none in the control group did.
- Patient-reported outcomes improved with the intervention, including quality of life, anxiety, and sleep.
- The diet group showed reductions in lipoprotein(a) and hemoglobin A1c but no changes in weight or cholesterol.
- Adherence strongly correlated with psoriasis improvement, suggesting a dose-response effect.
- Researchers cited limitations: small sample size, single-center design, and short follow-up.
- Larger multicenter studies with longer follow-up are needed to confirm findings and assess durability.
Source: JAMA Dermatology
