Lebrikizumab Meets Phase 3 End Points in Pediatric Atopic Dermatitis
Conexiant
March 17, 2026
Lebrikizumab met co-primary and key secondary end points in pediatric patients with moderate-to-severe atopic dermatitis in the Phase 3 ADorable-1 trial.
In the trial, 63% of patients on lebrikizumab achieved a 75% reduction in EASI score, compared to 22% in the placebo group.
The trial showed that 44% of lebrikizumab patients had an IGA score of 0 or 1, indicating clear skin, versus 15% with placebo.
Lebrikizumab's safety profile was consistent with previous studies, with common adverse events being upper respiratory infections and nasopharyngitis.
The ongoing ADorable-2 study will follow patients for up to 52 weeks, as lebrikizumab aims for potential label expansion for younger patients.
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