- Recent research challenges previous theories about the pathogenesis of hidradenitis suppurativa by suggesting a significant role of apocrine glands, particularly in follicular obstruction.
- Smaller apocrine glands and histological damage were observed in HS skin.
- Altered cell junction genes and enhanced signaling pathways indicate potential implications for immune activation and treatment strategies.
- The study emphasized a subset of patients with HS may have apocrine gland involvement.
- The limitations of the study include a small sample size and variable gland damage across patients.
Hidradenitis Suppurativa: Follicular Obstruction or Apocrine Glands?
Conexiant
January 13, 2025