The FDA said it is starting a process to remove fluoride supplements for children from the market, the latest federal action against the tooth-strengthening mineral.
U.S. Health Secretary Robert F. Kennedy Jr. has opposed adding the mineral to tap water, claiming that U.S. fluoridation levels are associated with numerous health issues, including cancer.
"Ending the use of ingestible fluoride is long overdue," said Kennedy.
The latest action targets ingestible fluoride supplements that are given to children who are at high risk of dental cavities, which the agency said are not approved by the FDA and have been shown to alter the gut microbiome.
The American Dental Association has reiterated its support for community water fluoridation to help prevent tooth decay.
Studies show that community water fluoridation reduces tooth decay by more than 25% in children and adults, even in an era with widespread availability of fluoride from other sources such as toothpaste, the association said.
The FDA has set a goal date of October 31 for completing a safety review and public comment period and for taking appropriate action regarding the removal of these products from the market.
In May, Utah became the first U.S. state to ban the use of fluoride in public water systems after Governor Spencer Cox's announcement that he would sign legislation to that effect.