April 16, 2025

Newer Glucose-Lowering Drugs Reduce CV Events in Older Adults

"Use of GLP1-RAs and SGLT-2is was associated with reduced rates of 3P-MACE and HHF compared to DPP-4is, independent of age" - findings from a Danish nationwide study of 35,679 patients aged 70 and older with T2D.

Conexiant

April 16, 2025

CONSORT 2025: Setting New Standards for Clinical Trial Reporting

"Readers should not have to infer what was probably done; they should be told explicitly." This principle drives the comprehensive CONSORT 2025 update, with its 7 new checklist items aimed at improving clinical trial transparency.

Conexiant

April 15, 2025

Mavacamten Misses Endpoints in nHCM Trial

Mavacamten's phase III trial for nonobstructive hypertrophic cardiomyopathy does not show significant improvement in functional capacity or symptoms, reflecting challenges in less severe populations. Bristol Myers Squibb plans to present full data at a future scientific meeting.

Reuters

April 15, 2025

Tenecteplase Matches Alteplase in Stroke Outcomes

In a registry-based study of 79,550 patients, tenecteplase showed comparable short-term safety and effectiveness to alteplase for acute ischemic stroke, with no significant differences in functional outcomes or hemorrhagic events.

Conexiant

April 14, 2025

Pecans May Lower Cholesterol, Triglycerides

Replacing usual snacks with 57 g/d of pecans for 12 weeks improved lipids and diet quality.

Conexiant

April 11, 2025

Combination Lipid Therapy Lowers CV Risk

Meta-analysis shows a 19% reduction in all-cause mortality with combination lipid-lowering therapy vs statin monotherapy in high-risk patients.

Conexiant

April 11, 2025

Relaxation Techniques Lower Blood Pressure in Short Term, Study

Most relaxation interventions were associated with short-term reductions in blood pressure among adults with hypertension, according to a network meta-analysis of 182 randomized trials.

Conexiant

April 10, 2025

Diagnosed ADHD Associated with Reduced Lifespan

Adults diagnosed with ADHD in the UK had shorter life expectancy than matched peers

Conexiant

April 10, 2025

Morning Coffee Consumption Linked to Lower Mortality Risk

“Drinking coffee in the morning may be more strongly associated with a lower risk of mortality than drinking coffee later in the day."

Conexiant