5 Key Takeaways

• 1

  20.1% of echocardiograms received different diastolic function grades when evaluated using the 2016 and 2025 ASE guidelines.

• 2

  The study analyzed 300,828 adult transthoracic echocardiograms performed between 2013 and 2022.

• 3

  Under the 2025 guidelines, 14.0% of studies were upgraded in diastolic dysfunction grading compared to the 2016 guidelines.

• 4

  The proportion of studies classified as having normal diastolic function decreased from 78.9% under 2016 to 73.8% under 2025.

• 5

  Older age, female sex, and higher left ventricular systolic function were associated with increased diastolic dysfunction grading using the 2025 guidelines.