5 Key Takeaways

• 1

  A randomized trial in Canada found similar mortality and readmission rates at 90 days for lactated Ringer’s and normal saline.

• 2

  The composite primary outcome of death or readmission within 90 days was 20% for lactated Ringer’s and 21% for saline.

• 3

  Mortality rates were 7% for the lactated Ringer’s group and 8% for the saline group, with readmissions around 15% for both.

• 4

  Subgroup analyses showed consistent results across various demographics, including patients with sepsis and traumatic brain injury.

• 5

  The trial, conducted at 7 hospitals, ended early due to COVID-19, impacting the ability to detect small differences.