5 Key Takeaways

• 1

  The study found that LDL cholesterol levels between 100 and 189 mg/dL were linked to the lowest long-term mortality risk in adults aged 50 to 89.

• 2

  Data from 177,860 adults indicated a U-shaped relationship between LDL cholesterol categories and mortality rates.

• 3

  Total cholesterol/HDL and triglycerides/HDL ratios were associated with long-term mortality, while LDL cholesterol had limited predictive value.

• 4

  The lowest risk for ASCVD events was also observed in the LDL cholesterol range of 100 to 189 mg/dL.

• 5

  The study's limitations included the inability to assess cause-specific mortality and potential biases from reverse causation.