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Conexiant chevron_right Cardiology chevron_right Large Trial Finds No Stroke Benefit From CEP Study
From the Journals

Large Trial Finds No Stroke Benefit From CEP, Study

A large U.K. trial found that routine use of cerebral embolic protection did not decrease the incidence of stroke within 72 hours among patients undergoing TAVI.

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  1. BHF PROTECT-TAVI trial involved 7635 aortic stenosis patients undergoing TAVI.
  2. Routine use of cerebral embolic protection did not reduce stroke within 72 hours post-procedure. 
  3. Disabling stroke occurred in 1.2% of patients in the CEP group and 1.4% in the control group.
  4. Mortality within 72 hours occurred in 0.8% of the CEP group and 0.7% of the control group.
  5. Serious adverse events occurred in 0.6% of the patients in the CEP group compared with 0.3% of those in the control group.
  6. Subgroup analysis and compliance-adjusted causal effect modeling showed no significant treatment effects. 

Source: The New England Journal of Medicine

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