5 Key Takeaways

• 1

  Frailty is more common in women hospitalized with acute myocardial infarction, but its mortality risk is greater in men.

• 2

  The study analyzed 931,133 patients with acute myocardial infarction in England and Wales from 2005 to 2019.

• 3

  Severe frailty was found in 16.7% of female patients and 10.4% of male patients, with men presenting more comorbidities.

• 4

  After adjustment, severe frailty increased 1-year mortality risk by 26% in men compared to women, with a 1.19% absolute risk difference.

• 5

  The findings suggest a need for tailored risk assessments that consider both frailty and sex in clinical evaluations.