- Common vascular risk factors like hypertension, diabetes, and hyperlipidemia were not associated with cerebrovascular pathologic changes in individuals aged 90 and older.
- Medication adherence was notably high, suggesting effective treatment might mitigate vascular risks in advanced age.
- The study found that the APOE-ε4 gene variant was associated with a higher likelihood of cerebral amyloid angiopathy.
- The research highlights potential gaps in understanding vascular risk management in this population.
- The study represents one of the largest prospective autopsy cohorts of individuals aged 90 and older.
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