5 Key Takeaways

• 1

  A combined measure of high-sensitivity C-reactive protein, LDL cholesterol, and lipoprotein(a) predicted cardiovascular events in healthy women over 30 years.

• 2

  The study analyzed data from 27,939 women with a median follow-up of 27.4 years, during which 3,662 major adverse cardiovascular events occurred.

• 3

  Increasing quintiles of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) were associated with higher 30-year cardiovascular risk.

• 4

  The greatest risk stratification was achieved by using all three biomarkers in combination, with higher hazard ratios for multiple biomarkers.

• 5

  The study's limitations included a predominantly White female cohort and the absence of repeated biomarker measurements.