Cardiac arrest survivors with complete neurologic recovery at discharge may have a 73.8% survival rate at 5 years, according to a recent study.
In the cohort study, published in JAMA Network Open and conducted in Sweden, investigators assessed long-term survival in patients following cardiac arrest, focusing on the association between neurologic recovery at discharge and survival outcomes. The study included 9,390 survivors who were evaluated using the Cerebral Performance Category (CPC) scale at hospital discharge: CPC 1 for complete recovery, CPC 2 for moderate disability, and CPC 3 or 4 for severe disability.
The median age of patients in the study was 69 years (interquartile range = 58–77 years). Males accounted for 69.7% of the patients, totaling 6,544 patients.
At discharge, 78.5% (n = 7,374) of the patients had complete neurologic recovery (CPC 1), 14.5% (n = 1,358) had moderate disabilities (CPC 2), and 7.0% (n = 658) experienced severe disabilities or were in a coma (CPC 3 or 4).
The results indicated that complete neurologic recovery (CPC 1) was associated with improved long-term survival compared with moderate (CPC 2) or severe disabilities (CPC 3 or 4). At 5 years, survival rates were 73.8% for CPC 1, 64.7% for CPC 2, and 54.2% for CPC 3 or 4. After adjusting for various factors, the hazard ratios for mortality were 1.57 for CPC 2 and 2.46 for CPC 3 or 4, relative to CPC 1. These associations were consistent in both out-of-hospital and in-hospital cardiac arrest subgroups.
Full disclosures can be found in the published study.