MRI-derived liver fat content closely predicted the risk of prediabetes and type 2 diabetes in adults with obesity, according to a Radiology study. Researchers analyzed data from 683 patients (mean age, 33 years) who underwent MRI and glucose tolerance testing. Each 1% rise in liver fat was tied to greater odds of abnormal glucose metabolism. Those with severe steatosis (25% or more PDFF) were over three times likelier to have dysglycemia than nonfatty participants. Elevated ALT and AST explained up to 39% of this link. Validation in 100 patients confirmed higher PDFF levels in those with diabetes.