October 04, 2024

Infant RSV Drug Plant Violated FDA Rules, Docs Show

Recent FDA documents uncover manufacturing issues at Thermo Fisher Scientific's U.S. plant, raising concerns about drug safety and regulatory compliance.

Reuters

October 03, 2024

High-Dose Antipsychotics Raise Pneumonia Risk

High-dose quetiapine (≥440 mg/d) was associated with the highest risk of pneumonia (AHR, 1.78) among antipsychotics in patients with schizophrenia, challenging previous beliefs about clozapine's singular risk profile.

Conexiant

October 01, 2024

WHO Backs Maternal Shot, Antibodies for Infant RSV Prevention

The World Health Organization recommends maternal vaccination and antibody therapy for preventing respiratory syncytial virus (RSV) in infants, with concerns raised around supply and treatment equity.

Reuters

September 27, 2024

New RBC Transfusion Guidelines: Restrictive Approach Prevails

The new guidelines recommend a restrictive RBC transfusion strategy for critically ill adults, including those with acute gastrointestinal bleeding and cardiac surgery. The guidelines advise against a restrictive strategy in acute coronary syndrome and suggest relying on expert opinion for isolated troponin elevation, while advising against permissive transfusion thresholds in septic shock.

Conexiant

September 24, 2024

High vs Low NPPV in COPD: Reduced Intubation Criteria, Same Intubation Rates

A recent study compared high-intensity noninvasive positive pressure ventilation (NPPV) with low-intensity NPPV in patients with chronic obstructive pulmonary disease. The high-intensity group had a lower likelihood of meeting intubation criteria, but the actual intubation rates did not differ significantly.

Conexiant

September 17, 2024

Proteomic Score Shows Potential in Predicting COPD Risk

A new proteomic risk score based on 32 blood proteins may predict an increased likelihood of developing chronic obstructive pulmonary disease and respiratory-related mortality, offering potential for early disease detection without the need for long-term spirometry monitoring.

Conexiant

September 17, 2024

Will Antibiotic-Resistant Deaths Surge by 2050?

Antibiotic resistance is set to cause over 39 million direct deaths worldwide in the next 25 years, with an additional 169 million fatalities indirectly linked—raising urgent questions about global preparedness.

Reuters

September 13, 2024

Teclistamab Shows Promise in Treating Refractory Autoimmune Diseases Like SLE in Case Reports

A recent study highlights the potential of teclistamab, a bispecific antibody, in treating refractory systemic lupus erythematosus and other autoimmune diseases, showcasing promising improvements in disease markers and clinical efficacy.

Conexiant

September 11, 2024

RSV Vaccine Reduces Hospitalization Risk in Adults Aged 60+

In response to these findings, the CDC updated its RSV vaccination guidance in June 2024.

Conexiant