Researchers developed and cross-validated ultrasound-based equations to estimate whole-body muscle mass in 211 healthy Caucasian adults, using magnetic resonance imaging as the reference standard and incorporating both muscle thickness and cross-sectional area measurements. Models combining thickness and cross-sectional area demonstrated the highest accuracy (adjusted R² up to 0.942; standard error ~1.7 kg), supporting ultrasound as a practical, noninvasive alternative for muscle mass assessment with potential applications in clinical evaluation of sarcopenia and related conditions.

Source: Journal of Cachexia, Sarcopenia and Muscle