Nonmenopausal females aged 40 to 54 years have a 48% higher risk of developing long COVID compared to males in the same age group, while menopausal females show a slightly lower but still elevated risk. The study, published in JAMA Network Open, revealed that gender, age, and menopausal status are significant factors in the risk of long COVID. The researchers emphasize the importance of investigating sex-specific mechanisms underlying long COVID, suggesting that factors such as age, hormonal status, and immune modulation may contribute to the observed differential risk.