- The phase III endTB trial confirmed the noninferiority of three all-oral regimens for treating patients with rifampin-resistant tuberculosis.
- The trial was conducted in multiple countries, including high-burden TB settings.
- The BCLLfxZ, BLMZ, and BDLLfxZ regimens were the most efficacious vs standard therapy.
- "The results of the endTB trial improve prospects for effective, simple, all-oral treatment for adults and children with this disease," study authors concluded.
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