- NHANES 2009–2018 analysis of 3,729 women examined obesity measures, inflammation, and asthma.
- Higher body mass index, body roundness index, and white blood cell counts increased asthma odds.
- Threshold effects: BMI above 25.3, BRI above 3.84, and WBC above 4.8 × 10⁹/L showed stronger associations.
- Women in the highest BRI quartile had nearly double the odds of asthma.
- Mediation analysis: white blood cells explained 9–11% of the obesity–asthma relationship.
- Study limits: cross-sectional design, self-reported asthma, and restriction to U.S. women.
Source: BMC Pulmonary Medicine