- Adults with both asthma and obstructive sleep apnea (OSA) had a 62% higher risk of intubation than those with asthma alone.
- OSA was linked to increased asthma exacerbations (relative risk [RR] 1.30), acute coronary syndromes (RR 1.35), and atrial fibrillation (RR 1.45) over 5 years.
- Patients with OSA required more bronchodilator and corticosteroid therapy (RR 1.24), suggesting greater disease burden.
- Propensity-matched data from 69 US health systems reinforce OSA as a key comorbidity influencing respiratory and cardiovascular outcomes in asthma.
- Researchers recommended routine screening for sleep-disordered breathing in patients with poorly controlled asthma, obesity, or cardiovascular comorbidities.
Source: Chest Annual Meeting 2025