- The study compared the impact of glucose-lowering medications on COPD exacerbations in patients with type 2 diabetes.
- SGLT-2 inhibitors and GLP-1 receptor agonists may be preferable to DPP-4 inhibitors for patients with type 2 diabetes and active COPD.
- The primary outcome was the first occurrence of a moderate or severe COPD exacerbation, defined as a filled prescription for oral glucocorticoids associated with an outpatient visit or hospitalization.
- The study highlighted the need for further clinical studies and trials to corroborate the findings.
- Potential for residual or unmeasured confounding was acknowledged by the authors.
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