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Conexiant chevron_right Pulmonary chevron_right Fluoroquinolones vs Amoxicillin Anaphylaxis Risk
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Fluoroquinolones vs Amoxicillin: Anaphylaxis Risk

Moxifloxacin carries the highest anaphylaxis risk among fluoroquinolones, while the entire drug class shows a lower risk than amoxicillin, Penn State researchers reported.

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  1. Moxifloxacin demonstrated the highest risk of anaphylaxis within the fluoroquinolone class.
  2. Current guidelines recommend challenging patients with an alternative drug within the same class when hypersensitivity occurs.
  3. The study focused specifically on oral and intravenous formulations of levofloxacin, ciprofloxacin, and moxifloxacin.
  4. Women comprised 60.5% of fluoroquinolone-associated anaphylaxis cases.
  5. The mean age of affected patients was 55 years.

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