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Conexiant chevron_right Pathology chevron_right Study Maps Delta Like Protein 3 and SEZ6 Across Tumor Types
From the Journals

Study Maps Delta-Like Protein 3 and SEZ6 Across Tumor Types

Researchers highlight distinct Delta-like protein 3 and seizure-related 6 homolog patterns in neuroendocrine tumors.

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  1. DLL3 and SEZ6 expressions are prominent in neuroendocrine neoplasms.
  2. High-grade tumors like lung NECs show significant DLL3 positivity.
  3. SEZ6 is most frequently expressed in medullary thyroid carcinomas.
  4. The study analyzed 213 specimens, including NENs and non-NENs.
  5. A semi-quantitative H-score was used to evaluate staining intensity.

Source: Endocrine Pathology

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