July 15, 2025

Genetic Markers Don’t Guide RA Drug Choice

A large UK study found no significant difference in treatment effectiveness between abatacept and adalimumab for rheumatoid arthritis, regardless of patients’ HLA-DRB1 genetic profiles.

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July 15, 2025

Fibrinogen Concentrate Reduces Blood Loss in Surgery

In a phase 3 trial, a purified human fibrinogen concentrate reduced intraoperative blood loss and lowered thromboembolic risks compared with fresh frozen plasma or cryoprecipitate during major surgeries.

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July 15, 2025

Cementless Knee Implants Show Superior Outcomes in Patients With Obesity

A new review comparing knee implant methods in obese patients finds cementless fixation may improve implant survival and reduce loosening compared with cemented approaches, especially in patients with BMI ≥35 kg/m².

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July 15, 2025

Methotrexate Shows No Knee OA Symptom Benefit, Study Finds

A 52-week randomized clinical trial found no significant difference between methotrexate and placebo in reducing pain or effusion-synovitis in patients with inflammatory knee osteoarthritis.

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July 10, 2025

Tramadol Carries Lowest Constipation Risk Among Opioids

The UK hospital study of over 80,000 patients found that certain opioids, including morphine and oxycodone, carried a higher risk of severe constipation compared with others.

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July 08, 2025

Mediterranean Diet’s 30-Year Legacy

A sweeping 30-year review confirms the Mediterranean-style diet lowers risks of heart disease, diabetes, cancer, and cognitive decline—while supporting global sustainability.

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July 08, 2025

No Safe Level for Processed Foods

A meta-analysis finds no safe level of processed meat, sugary drinks, or industrial trans fats—each linked to increased chronic disease risk.

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July 08, 2025

Higher BMI, Heart Disease Raise Cancer Risk 

Obesity raises breast cancer risk more sharply in postmenopausal women with heart disease, per data from 168,000+ women in two major European cohorts.

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July 08, 2025

New Obesity Framework Reclassifies 1 in 5 Adults

EASO’s expanded obesity definition incorporating waist-to-height ratio and comorbidities reclassifies 18.8% of overweight adults, but mortality benefits remain uncertain.

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