- Inflammatory orbital diseases involve the infiltration of inflammatory cells within the orbital fat compartment.
- Orbital fat exhibits distinct metabolic properties which contribute to immune responses and inflammation in various conditions.
- Management of inflammatory orbital diseases often involves corticosteroids, immunosuppressive agents, and surgical interventions.
- However, emerging strategies include the use of orbital fat-derived stem cells and novel approaches such as orbital decompression surgery and targeted monoclonal antibody therapy.
- Research into the immunologic activity and structural properties of orbital fat could lead to improved management of these conditions.
Source: Ophthalmology and Therapy
