In a retrospective study, researchers evaluated the outcomes of trabeculectomy with mitomycin C in African ancestry patients with primary open-angle glaucoma—a population that is disproportionately impacted by glaucoma. The study found that while trabeculectomy resulted in substantial reductions in intraocular pressure and medication use, complications were common, and younger age, family history of glaucoma, and worse preoperative visual acuity were associated with higher failure rates. The investigators emphasized the complexities of trabeculectomy outcomes in African ancestry populations, as well as the need for precision-based approaches to glaucoma management.

Source: Journal of Glaucoma