- Study reveals a decrease in retinal capillary perfusion in patients with long COVID and persistent neurologic symptoms.
- Optical coherence tomography angiography (OCT-A) was used to observe microvascular involvement.
- Reductions in vessel length density correlate with severity of neurocognitive symptoms.
- Retinal OCT-A imaging could serve as a noninvasive biomarker for small vessel disease in long COVID.
- Findings may support hypotheses of central nervous system damage in SARS-CoV-2 infections.
- The study's small sample size limited generalizability of findings and correlations with NIH Toolbox and PROMIS measures.
- No correlations between COVID-19 vaccines and retinal microvasculature were found.
Source: Journal of Imaging