March 12, 2024

HPV-Associated Oropharyngeal Cancer: Intratreatment FDG-PET Response as a Biomarker for De-escalation of Radiotherapy

The use of imaging midtreatment for HPV-associated oropharyngeal squamous cell carcinoma may guide the use of deintensified chemoradiotherapy, according to a phase II study presented at the 2024 Multi...

The ASCO Post

September 14, 2023

Pembrolizumab Plus Chemoradiation Therapy Falls Short in Locally Advanced Head and Neck Cancer

Pembrolizumab plus chemoradiation therapy failed to demonstrate a statistically significant improvement in event-free survival vs chemoradiation therapy alone in patients with locally advanced head an...

The ASCO Post

September 26, 2023

Personalized Biomarker-Based Umbrella Trial in Recurrent or Metastatic HNSCC

Learn more about the results of a personalized biomarker-driven umbrella trial for the treatment of patients with platinum-refractory recurrent and/or metastatic head and neck squamous cell carcinoma ...

The ASCO Post

March 05, 2024

HPV-Associated Oropharyngeal Cancer: Adjuvant Treatment Deintensification

Postoperative adjuvant therapy—both chemoradiotherapy and radiotherapy alone—for HPV-associated oropharyngeal squamous cell carcinoma may be safely de-escalated, according to results presented at the ...

The ASCO Post

September 14, 2023

Dysphagia-Optimized vs Standard IMRT in Newly Diagnosed Patients With Head and Neck Cancer

In the phase III DARS study reported in The Lancet Oncology, Nutting et al found that dysphagia-optimized intensity-modulated radiotherapy (IMRT) was associated with improved patient-reported swallowi...

The ASCO Post

February 28, 2024

Risk of Stroke in Survivors of Head and Neck Cancer

A study from Singapore evaluated the risk of stroke among survivors of head and neck cancer compared with the general population.

The ASCO Post

January 25, 2023

Expert Point of View: Renata Ferrarotto, MD

Dr. Renata Ferrarotto of The University of Texas MD Anderson Cancer Center provides insight into the encouraging efficacy results with cabozantinib plus atezolizumab in recurrent or metastatic head and neck squamous cell carcinoma, emphasizing the need to identify biomarkers for clinical benefit.

The ASCO Post

February 09, 2023

Case Study: Otolaryngologist’s Cultural Intuition Finds Source of Patient’s Hearing Loss

Hearing loss may indicate a range of diagnoses and potential comorbidities. However, for some patients, cultural and environmental factors such as where a patient grew up may point to sources of hearing loss, including life-threatening cancers.

Keck Medicine of USC

July 31, 2024

Recurrent/Metastatic HNSCC: Pembrolizumab Plus Carboplatin and Paclitaxel

The phase IV KEYNOTE-B10 trial of pembrolizumab plus carboplatin and paclitaxel in the first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma showed that the regimen produc...

The ASCO Post