June 20, 2025

Symptom-Detected Breast Cancers May Be Linked to Higher Mortality and Advanced Disease Risk

Whether a patient’s breast cancer was detected through symptoms or routine screening mammography significantly affected their risk for advanced disease or death, according to a study published in Radi...

The ASCO Post

June 20, 2025

How a Commonly Inherited Genetic Alteration Is Driving Breast Cancer Metastasis and Predicting Survival

A common germline variant in the proprotein convertase subtilisin/kexin type 9 (PCSK9) (rs562556, V474I) gene rather than a mutation in a breast cancer tumor may be the driving force in significantly ...

The ASCO Post

June 17, 2025

BRCA Mutations Could Increase Risk of Rare Lymphoma Among Women Who Received Textured Breast Implants During Breast Cancer Treatment

The risk of developing breast implant–associated anaplastic large-cell lymphoma (ALCL) could be higher among women with breast cancer and BRCA1 or BRCA2 mutations who received textured breast implants...

The ASCO Post

June 16, 2025

Collaborative Strategy Involving AI, Human Task-Sharing Could Help Minimize Mammogram Costs

Ahsen et al evaluated the economic feasibility of incorporating artificial intelligence (AI) into mammography screening within health-care settings, considering full or partial integration. The findin...

The ASCO Post

June 16, 2025

Chemotherapy-Free Triplet in Previously Treated HR-Positive, HER2-Positive Advanced Breast Cancer

In a phase IIa study reported in The Lancet Oncology, Escrivá-de-Romani et al evaluated whether the chemotherapy-free triplet of the HER2-targeted bispecific antibody zanidatamab plus palbociclib and ...

The ASCO Post

June 16, 2025

Sacituzumab Govitecan and Pembrolizumab Improve Disease Control in Advanced PD-L1–Positive Triple-Negative Breast Cancer

Results from an international phase III clinical trial show that treatment with sacituzumab govitecan and pembrolizumab helps patients with unresectable, locally advanced or metastatic PD-L1–positive ...

The ASCO Post

June 16, 2025

CAP Issues New and Updated Cancer Protocols

New protocols for endocrine tumors and updated existing protocols for breast cancer diagnoses are now available from the College of American Pathologists (CAP).

The ASCO Post

June 16, 2025

Raising Awareness of Inflammatory Breast Cancer

In late January 2013, while playing with my young son, I noticed my left breast seemed slightly larger than my right breast. Although, at the time, I had no idea this type of swelling is a hallmark of...

The ASCO Post

June 16, 2025

Breast Parenchymal Phenotypes and Risk of Breast Cancer

Six parenchymal phenotypes were established that may be associated with a higher risk of developing breast cancer. Studies of these phenotypes identified by radiomics on mammograms demonstrated that t...

The ASCO Post