March 26, 2025

Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common leukemia in the Western hemisphere. The majority of patients who require treatment are older than age 65. The treat...

The ASCO Post

March 26, 2025

HER2-Selective TKI in Advanced Solid Tumors with HER2 Alterations

In a phase Ia/Ib study (Beamion LUNG-1) reported in the Journal of Clinical Oncology, Heymach et al evaluated the safety profile and activity of zongertinib in patients with HER2-altered solid tumors....

The ASCO Post

March 26, 2025

Hypofractionated Radiotherapy in Prostate Cancer

In an individual patient data meta-analysis, investigators studied whether isodose and dose-escalated moderately hypofractionated radiotherapy exhibited similar efficacy vs conventionally fractionated...

The ASCO Post

March 26, 2025

Sex Differences in Waist Circumference vs BMI as Risk Factors for Obesity-Related Cancers

New findings suggest that waist circumference may be a more effective risk marker for obesity-related cancers than body mass index (BMI) in male patients, emphasizing the crucial role of abdominal adiposity in cancer risk.

The ASCO Post

March 26, 2025

FDA Approves Cabozantinib for pNET and epNET

Today, the FDA approved the tyrosine kinase inhibitor cabozantinib (Cabometyx) for adult and pediatric patients aged 12 years and older with previously treated, unresectable, locally advanced or metas...

The ASCO Post

March 26, 2025

Pembrolizumab Plus Chemotherapy: New Standard of Care in Locally Advanced Cervical Cancer?

Updated findings from the second planned interim analysis of the phase III ENGOT-cx11/GOG-3047/KEYNOTE-A18 study solidify the PD-1 inhibitor pembrolizumab plus concurrent chemoradiotherapy, followed b...

The ASCO Post

March 26, 2025

Are New-Onset Type 2 Diabetes and Obesity-Related Cancers Linked?

A new diagnosis of type 2 diabetes may be linked to a subsequent increased risk of developing some obesity-related cancers, according to findings presented at the European Congress on Obesity (ECO) 20...

The ASCO Post

March 25, 2025

Can a Urine Test Minimize Postoperative Scans for RCC Recurrence?

Researchers examined whether a urine test could accurately detect clear cell renal cell carcinoma recurrence at an early stage, according to findings presented at the European Association of Urology (...

The ASCO Post

March 25, 2025

TB Vaccination Could Enhance BCG Response in Patients With Non–Muscle-Invasive Bladder Cancer, Study Finds

“We expected that the RUTI vaccine would improve the immune response for patients, but we didn’t know what effect this might have on cancer progression over 5 years. It was very surprising for us to s...

The ASCO Post