July 23, 2025

Polatuzumab Vedotin–Based Regimen Improves Overall Survival in Refractory DLBCL

Combining the CD79b-directed antibody-drug conjugate polatuzumab vedotin-piiq with rituximab, gemcitabine, and oxaliplatin (R-GemOx) significantly improved survival outcomes in patients with transplan...

The ASCO Post

July 22, 2025

Chinese Herbal Medicine for Improving Adjuvant Chemotherapy Completion in Patients With Colon Cancer

Guest Editor’s Note: Although guidelines recommend adjuvant combination chemotherapy for patients with stage II and III colon cancer who are at high risk of disease recurrence, fewer than 50% complete...

The ASCO Post

July 22, 2025

Updated Results Confirm Benefit of Combination Regimen in BRAFV600E–Mutated Metastatic Colorectal Cancer

Patients with previously untreated BRAF V600E–mutated metastatic colorectal cancer who receive the BRAF inhibitor encorafenib and the EGFR inhibitor cetuximab plus mFOLFOX6 (modified leucovorin, fluor...

The ASCO Post

July 22, 2025

Adjuvant Use of Atezolizumab Plus Chemotherapy in DNA Mismatch Repair–Deficient Colon Cancer

For the adjuvant treatment of stage III colon cancer with DNA mismatch repair–deficient (dMMR) tumors, the addition of the checkpoint inhibitor atezolizumab to standard chemotherapy significantly impr...

The ASCO Post

July 17, 2025

Upfront Radical Cytoreductive Surgery Extends Progression-Free Survival in Advanced Ovarian Cancer

The TRUST trial is the first phase III randomized study to show improved progression-free survival for primary cytoreductive surgery compared with interval surgery without compromising short-term or l...

The ASCO Post

July 14, 2025

Improving Use of Cytomegalovirus Negative and Irradiated Blood Products in an Outpatient Oncology Clinic

A new transfusion algorithm significantly enhances the safety of blood product transfusions for at-risk patients with hematologic malignancies.

JADPRO

July 14, 2025

Dual Menin and KAT6A/7 Inhibition Improves Outcomes in NUP98-Rearranged Pediatric AML Models

A combination of menin inhibition and KAT6A/7 inhibition significantly improved survival for pediatric acute myeloid leukemia (AML) in AML model systems, according to findings published in Cancer Disc...

The ASCO Post

July 14, 2025

Can Planned C-Sections Increase the Risk of Childhood ALL?

A study that included nearly 2.5 million children born in Sweden found the risk of ALL was 21% higher in children born by planned cesarean section (C-section) compared with children born vaginally, al...

The ASCO Post

July 10, 2025

Relacorilant and Nab-Paclitaxel in Platinum-Resistant Ovarian Cancer

In a phase III trial (ROSELLA) reported in The Lancet, Olawaiye et al examined the survival benefit of adding relacorilant to nab-paclitaxel in women with platinum-resistant ovarian cancer. Relacorila...

The ASCO Post