1. The U.S. Preventive Services Task Force reaffirms the A recommendation for universal screening for syphilis infection in all pregnant individuals.
2. There has been a significant increase in congenital syphilis rates, with notable racial and ethnic disparities.
3. Almost 90% of new congenital syphilis cases could have been prevented with timely testing and treatment.
4. Screening involves a blood test that detects antibodies reflecting infection with the causative organism of syphilis.
5. The CDC recommends parenteral penicillin G as the only treatment for syphilis during pregnancy.
6. Future research is needed to evaluate the benefits and harms of repeat screening later in pregnancy and to address disparities in congenital syphilis incidence.
7. The recommendation is based on reaffirmation evidence update with a focus on the benefits and harms of syphilis screening during pregnancy.

Source: JAMA