- Risk of developing gestational trophoblastic neoplasia (GTN) after complete molar pregnancy found to be low when hCG levels normalize within 56 days of evacuation.
- GTN risk percentages dependent on timing of hCG normalization.
- Study suggests individualized surveillance protocols based on hCG normalization timing.
- Most GTN cases diagnosed after standard 6-month surveillance period; common presenting symptoms include elevated hCG levels and vaginal bleeding.
- Metastatic disease at diagnosis seen in about 26% of cases, often affecting lungs, brain, or vagina.
- Some cases involved GTN originating from the original molar pregnancy.
- Revised surveillance protocols could reduce unnecessary follow-up and improve family planning.
Source: BMJ Medicine