- Hormone therapy with conjugated equine estrogens (CEE) alone or combined with medroxyprogesterone acetate (MPA) affects cardiovascular biomarkers in postmenopausal women.
- CEE alone and CEE plus MPA showed reductions in LDL cholesterol, increases in HDL cholesterol, and lowered lipoprotein(a) levels.
- However, triglycerides and clotting-related factors increased with hormone therapy.
- Hormone therapy did not reduce the risk of coronary heart disease.
- The study recommends considering overall cardiovascular outcomes to weigh the benefits and risks of hormone therapy.
Source: Obstetrics and Gynecology